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Biomedical Signals and Sensors I

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  • Saadedin
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    • Sep 2018 
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    Biomedical Signals and Sensors I: Linking Physiological Phenomena and Biosignals













    Preface

    The present two volume set focuses on the interface between physiologic

    mechanisms and diagnostic human engineering. A multitude of biomedical sensors

    are commonplace in clinical practice today. The registered biomedical signals,

    which will be referred to as biosignals, reflect vital physiologic phenomena and are

    relevant not only for the pre-screening and diagnosis of maladies but also for therapy

    and follow-up treatment. For instance, the diagnosis of sleep apnea, i.e., abnormal

    cessation of respiration during sleep, requires the monitoring of a complete set of

    sleep and respiratory variables with at least eight different sensors distributed over

    the entire body.



    In order to adequately apply biomedical sensors and reasonably interpret the

    corresponding biosignals, a proper understanding of the physiologic phenomena

    involved, their influence on the registered biosignals, and the technology behind the

    sensors is critical. Moreover, a nearly unlimited diversity of biosignals emphasizes

    the need for a strategic approach in the genesis of biosignals, including a profound

    understanding of fundamentally different mechanisms in a biosignal’s generation.

    From a strategic point of view, biosignal generation involves the biosignal

    formation path from the biosignal source at the physiological level, to biosignal

    propagation in the body, to biosignal transmission in the sensor up to its conversion

    to a, usually electric, signal. To give an example, heart sounds, an acoustic biosignal,

    are created by the closure of heart valves, which constitutes the biosignal source.

    Sound attenuation in the thoracic tissue represents the propagation mechanism.

    Amplification and filtering of the heart sounds in the chestpiece (of the stethoscope)

    reflect biosignal transmission effects in the sensor, with biosignal conversion being

    performed by a microphone at the output of the chestpiece.



    The first volume is focused on the interface between physiologic mechanisms

    and the resultant biosignals, whereas the second volume is devoted to the interface

    between biosignals and biomedical sensors. Unlike other contributions, this book

    deals differently on the subject of either specific physiologic mechanisms or

    specific engineering aspects pertaining to particular biomedical sensors, since it

    emphasizes the interface between them. Both volumes systematically describe basic

    mechanisms of biosignal formation while electric, acoustic, optic, and mechanic

    biosignals are considered in depth.





    In the given volume, the physiologic mechanisms determining biosignals are

    described from the basic cellular level—as the place of origin of each and every

    biosignal—up to their advanced mutual coordination level, e.g., during sleep.

    It allows a physiologically accurate interpretation and comprehensive analysis of

    the biosignals. The resultant biosignals are discussed within the scope of vital and

    common physiologic phenomena to foster their understanding and comprehensive

    analysis.





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