Biomedical Nanotechnology - Neelina H. Malsch
Preface
In this book, we present the state of the art of nanotechnology research intended
for applications in biomedical technologies in three subfields: nanodrugs and drug
delivery inside the body; prostheses and implants; and diagnostics and screening
technologies for laboratory use. For each of these three subfields, we explore the
relevant developments in research.
Nanoparticles such as nanotubes and quantum dots are increasingly applied as
drug delivery vehicles. Applications may include gene therapy, cancer treatments,
and treatments for HIV and other diseases for which no cures presently exist.
Implanted drug delivery or monitoring devices can also include nanostructured
materials. Prostheses and implants include nanostructured materials. For example,
hip replacements can be made to fit better into the body if coated with nanostructured
materials. Nerve tissue can be made to grow along small silicon structures, and this
may help paralyzed patients. Nanotechnologies may also contribute to electronic
eyes and ears. The research on implants and prostheses focuses on two main directions:
(1) biological nanostructures that put biological molecules and tissues in a
strait jacket to grow into new structures and (2) biomimetic nanotechnology that
starts with physical and chemical structures and aims for a completely new
material.
Diagnostics and screening technologies include cantilever biochemical sensors,
different types of scanning probe microscopes, lab-on-a-chip techniques, and biosensors.
Nanoscience and nanotechnology focus on connecting living materials and electronics
as well as on imaging and manipulating individual molecules.
We place these developments in social and economic contexts to assess the
likelihood of uptake of these technologies and their relevance to the world’s most
pressing health needs. Do real needs and markets exist for these devices? We also
include a chapter exploring potential risks. The developments in the life science
technologies involving GMOs, cloning, and stem cell research have shown that
unexpected public concern may slow acceptance of new technologies. For nanotechnology,
the public debate is just emerging.
Researchers, government officials, and industrialists are actively
attempting to assess the risks and redirect research toward the
technologies consumers want and away from what the public will not accept.
The scope of this book includes scientific and technological details along with
detailed discussions of social and economic contexts. The intended audience includes
researchers active in nanoscience and technology in industry and academia, medical
professionals, government officials responsible for research, innovation, health care,
and biodefense, industrialists in pharmaceutical and biomedical technology, nongovernmental
organizations interested in environmental, health care, or peace issues, students,
and interested lay persons. We assume readers have academic training, but no
expertise in nanotechnology.
Release Notes
Biomedical nanotechnology is one of the fastest-growing fields of research
across the globe. However, even the most promising technologies may never
realize their full potential if public and political opinions are galvanized
against them, a situation clearly evident in such controversial fields as
cloning and stem cell research. Biomedical Nanotechnology presents state-of-the
-art research in the field and also considers the socio-political risks and
perceptions of this important science. Contributed by prominent experts in this
expansive and interdisciplinary field, Biomedical Nanotechnology examines
developments in three sub-fields: nanodrugs and drug delivery; prostheses and
implants; and diagnostics and screening technologies. The authors compare new
capabilities introduced by nanotechnology to traditional methods of release,
target, and controlled drug delivery in the body. They also consider the
challenge of understanding and controlling the biological processes involved
upon implantation and discuss nanoscale sensors for biological chemical
detection and biodefense. The book concludes with individual chapters devoted to
the social and economic context of nanotechnologies and to their potential risks
and possible solutions. By outlining cutting-edge research in the context of
pressing global medical needs and potential risks, this authoritative reference
supplies a holistic treatment of biomedical nanotechnology that enables us to
understand its implications and decide the best way to move forward.
Table of Contents
Introduction
Converging technologies
Nanotechnology and biomedicine
Ch. 1 Trends in biomedical nanotechnology programs worldwide 1
Ch. 2 Nanotechnology and trends in drug delivery systems with self-assembled
carriers 29
Ch. 3 Implants and prostheses 41
Ch. 4 Diagnostics and high throughput screening 75
Ch. 5 Nano-enabled components and systems for biodefense 113
Ch. 6 Social and economic contexts : making choices in the development of
biomedical nanotechnology 145
Ch. 7 Potential risks and remedies 177
Product Details
* ISBN: 0824725794
* ISBN-13: 9780824725792
* Format: Hardcover, 232pp
* Publisher: CRC Press
* Pub. Date: April 2005
Download
*
Preface
In this book, we present the state of the art of nanotechnology research intended
for applications in biomedical technologies in three subfields: nanodrugs and drug
delivery inside the body; prostheses and implants; and diagnostics and screening
technologies for laboratory use. For each of these three subfields, we explore the
relevant developments in research.
Nanoparticles such as nanotubes and quantum dots are increasingly applied as
drug delivery vehicles. Applications may include gene therapy, cancer treatments,
and treatments for HIV and other diseases for which no cures presently exist.
Implanted drug delivery or monitoring devices can also include nanostructured
materials. Prostheses and implants include nanostructured materials. For example,
hip replacements can be made to fit better into the body if coated with nanostructured
materials. Nerve tissue can be made to grow along small silicon structures, and this
may help paralyzed patients. Nanotechnologies may also contribute to electronic
eyes and ears. The research on implants and prostheses focuses on two main directions:
(1) biological nanostructures that put biological molecules and tissues in a
strait jacket to grow into new structures and (2) biomimetic nanotechnology that
starts with physical and chemical structures and aims for a completely new
material.
Diagnostics and screening technologies include cantilever biochemical sensors,
different types of scanning probe microscopes, lab-on-a-chip techniques, and biosensors.
Nanoscience and nanotechnology focus on connecting living materials and electronics
as well as on imaging and manipulating individual molecules.
We place these developments in social and economic contexts to assess the
likelihood of uptake of these technologies and their relevance to the world’s most
pressing health needs. Do real needs and markets exist for these devices? We also
include a chapter exploring potential risks. The developments in the life science
technologies involving GMOs, cloning, and stem cell research have shown that
unexpected public concern may slow acceptance of new technologies. For nanotechnology,
the public debate is just emerging.
Researchers, government officials, and industrialists are actively
attempting to assess the risks and redirect research toward the
technologies consumers want and away from what the public will not accept.
The scope of this book includes scientific and technological details along with
detailed discussions of social and economic contexts. The intended audience includes
researchers active in nanoscience and technology in industry and academia, medical
professionals, government officials responsible for research, innovation, health care,
and biodefense, industrialists in pharmaceutical and biomedical technology, nongovernmental
organizations interested in environmental, health care, or peace issues, students,
and interested lay persons. We assume readers have academic training, but no
expertise in nanotechnology.
Release Notes
Biomedical nanotechnology is one of the fastest-growing fields of research
across the globe. However, even the most promising technologies may never
realize their full potential if public and political opinions are galvanized
against them, a situation clearly evident in such controversial fields as
cloning and stem cell research. Biomedical Nanotechnology presents state-of-the
-art research in the field and also considers the socio-political risks and
perceptions of this important science. Contributed by prominent experts in this
expansive and interdisciplinary field, Biomedical Nanotechnology examines
developments in three sub-fields: nanodrugs and drug delivery; prostheses and
implants; and diagnostics and screening technologies. The authors compare new
capabilities introduced by nanotechnology to traditional methods of release,
target, and controlled drug delivery in the body. They also consider the
challenge of understanding and controlling the biological processes involved
upon implantation and discuss nanoscale sensors for biological chemical
detection and biodefense. The book concludes with individual chapters devoted to
the social and economic context of nanotechnologies and to their potential risks
and possible solutions. By outlining cutting-edge research in the context of
pressing global medical needs and potential risks, this authoritative reference
supplies a holistic treatment of biomedical nanotechnology that enables us to
understand its implications and decide the best way to move forward.
Table of Contents
Introduction
Converging technologies
Nanotechnology and biomedicine
Ch. 1 Trends in biomedical nanotechnology programs worldwide 1
Ch. 2 Nanotechnology and trends in drug delivery systems with self-assembled
carriers 29
Ch. 3 Implants and prostheses 41
Ch. 4 Diagnostics and high throughput screening 75
Ch. 5 Nano-enabled components and systems for biodefense 113
Ch. 6 Social and economic contexts : making choices in the development of
biomedical nanotechnology 145
Ch. 7 Potential risks and remedies 177
Product Details
* ISBN: 0824725794
* ISBN-13: 9780824725792
* Format: Hardcover, 232pp
* Publisher: CRC Press
* Pub. Date: April 2005
Download
*