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Improved Signal and Image Interpolation in Biomedical Applications

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  • Saadedin
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    • Sep 2018 
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    Improved Signal and Image Interpolation in Biomedical Applications:

    The Case of Magnetic Resonance Imaging (MRI)

    Carlo Ciulla

    Lane College, USA









    Preface

    OVERVIEW OF THE SUBJECT MATTER

    “If I am anything, which I highly doubt, I have made myself so by hard work.” Isaac Newton

    This book presents a novel theoretical framework for the improvement of the interpolation error from which is derived a

    unified

    methodology applied to several interpolation paradigms: two and three-dimensional linear,

    one-dimensional quadratic and cubic B-Splines, Lagrange, and Sinc. Advances are

    made to derive a framework that is unifying in its purpose and that thus achieves improvement

    of the approximation properties of the interpolation function regardless to its dimensionality or

    degree. The framework proposes a mathematical formulation, which consequentially to its



    developmental approach formulates interpolation error improvement

    as dependent from the joint information content of node intensity and the

    second order derivative of the interpolation function. From the theory

    herein developed, the mathematical formulation is derived by two



    main intuitions called the Intensity-Curvature Functional and the

    Sub-pixel Efficacy Region, and these are such to set the grounds for the

    improvement of the interpolation error. From the theory it descends that given

    a location where the interpolation function ought to estimate the value

    of the unknown signal, a novel sub-pixel (intra-node) re-sampling location

    is determined which varies locally pixel-by-pixel (node-by-node). The novel

    theory asserts and demonstrates by a-posteriori knowledge, that the interpolation

    error improvement can be achieved based on the joint information content of the

    node intensity and the second order derivative of the interpolation function.

    Consequentially to the formulation, re-sampling is performed locally at locations that are

    variable depending on the signal intensity at the neighborhood and local curvature of the interpolator

    .



    The book initiates presenting two mathematical intuitions and given that absolute

    truth cannot be reached by them, the intuitions serve the purpose to derive novel conceptions of

    interpolation error improvement. These conceptions are determined during a process driven

    through deduction and thus a theoretical framework is presented. The boundary

    of the truth determined through the mathematical intuitions in explaining interpolation

    error improvement are empirically tested. The

    purpose of the theory is that of unifying under the same approach interpolators of

    diverse degree and dimensionality such to determine novel interpolation functions so





    called: SRE-based interpolation functions, which possess improved approximation characteristics. The bridging concept between SRE-based and classic interpolation functions is the local curvature of the function as expressed by the second order derivative. There are extended mathematical descriptions of the theory with detailed formulations to conceptualize the steps of the approach. Also, improved interpolation functions are validated experimentally by a motion correction paradigm.





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