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Biomolecular Sensing Processing and Analysis - Rashid Bashir and Steve Wereley

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  • Saadedin
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    • Sep 2018 
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    Biomolecular Sensing Processing and Analysis - Rashid Bashir and Steve Wereley







    Preface

    BioMEMS and its extensions into biomedical nanotechnology have tremendous potential

    both from a research and applications point of view. Exciting strides are being made at

    intersection of disciplines and BioMEMS and biomedical nanotechnology is certainly one

    of these very interdisciplinary fields, providing many opportunities of contribution from

    researchers from many disciplines. In the specific areas of bimolecular sensing, processing

    and analysis, BioMEMS can play a critical role to provide the various technology platforms

    for detection of cells, microorganisms, viruses, proteins, DNA, small molecules, etc. and

    the means to interface the macroscale realm to the nanoscale realm.



    We are very pleased to present volume 4 in the Handbook of BioMEMS and Biomedical

    Nanotechnology, published by Kluwer Academic Press. This volume contains 18 chapters

    focused on ‘Biomolecular Sensing, Processing and Analysis’, written by experts in the field

    of BioMEMS and biomedical nanotechnology. The chapters are groups into three broad

    categories of Sensors and Materials, Processing and Integrated Systems, and Microfluidics.

    Prof. Taun Vo-Dinh from Oakridge National Labs begins the Sensors and Materials

    section by providing a review of biosensors and biochips. This review is followed by an

    example of mechanical cantilever sensor work described by Prof. Arun Majumdar’s group

    at UC Berkeley and Prof. Tom Thundat at Oakridge National Laboratory. An example of

    a nano-scale sensor electrical sensor, an artificial pore, integrated in a microscale device

    is presented next by Prof. Lydia Sohn’s group at UC Berkeley. Cell based sensors are an

    important class of electrical sensors and Profs. Cengiz Ozkan and Mihri Ozkan at UC

    Riverside present a review of their work in this area. These chapters on sensors are followed

    by a review chapter on silicon and glass BioMEMS processing by Prof. Nam Trung Nguyen

    at Nanyang Technological University. Polymers and hydrogels are an important class of

    bioMEMS materials and Profs. Nicholas Peppas at UT Austin and Zach Hilt at University

    of Kentucky provide a review chapter in this area to close off this section.



    The Processing and Integrated Systems section is focused on means to manipulate

    biological and fluidic samples in BioMEMS device and examples of integrated BioMEMS

    systems. Prof. Abe Lee from UCIrvine presents a reviewof magnetohydrodynamic methods

    and their utility in BioMEMS and micro-total-analysis (µTAS) systems. Dielectrophoresis

    (DEP) is being increasing used at the microscale and in BioMEMS applications and Prof.





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