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Optimization and Data Analysis in Biomedical Informatics

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    Optimization and Data Analysis in Biomedical Informatics









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    OPTIMIZATION AND DATA ANALYSIS IN BIOMEDICAL INFORMATICS



    PUBLISHER....: SPRINGER

    LANGUAGE......: ENGLISH



    FORMAT.......: PDF

    AUTHOR.......: PANOS M. PARDALOS - DISKS.........: 01

    THOMAS F. COLEMAN

    PETROS XANTHOPOULOS







    This volume covers some of the topics that are related to the rapidly growing

    field of biomedical informatics. In June 11-12, 2010 a workshop entitled

    `Optimization and Data Analysis in Biomedical Informatics' was organized at

    The Fields Institute. Following this event, invited contributions were gathered

    based on the talks presented at the workshop, and additional invited chapters

    were solicited from leading experts. In this publication, the authors share

    their expertise in the form of state-of-the-art research and review chapters,

    bringing together researchers from different disciplines and emphasizing the

    value of mathematical methods in the areas of clinical sciences.



    This work is targeted to applied mathematicians, computer scientists,

    industrial engineers, and clinical scientists who are interested in exploring

    emerging and fascinating interdisciplinary topics of research. It is designed

    to further stimulate and enhance fruitful collaborations between scientists

    from different disciplines.?





    Preface

    As science and society as a whole become more and more information intensive,

    there is an urgent need to develop, create, and apply new algorithms and methods

    to model, manage, and interpret this information. This is nowhere more evident

    than in biomedicine, where clinicians and scientists are routinely faced with

    conflicting (sometimes contradictory) sources of knowledge, in addition to the

    overwhelming and ever increasing stream of data. Bioinformatics and the -omics

    (genomics, proteomics, etc.) herald the advent of a new era and a new paradigm for

    scientific and, in particular, biomedical research. Together with the tools developed

    in optimization theory and the mathematical sciences, we are at a crossroads, where

    a more fundamental understanding of biological processes is within our grasp. This

    understanding will certainly pave the way for a more systematic attack on the

    mechanics of diseases, as opposed to a naive treatment of their symptoms (which

    has been the hallmark of classical medicine). It seems clear that there is an urgent

    need in biomedicine for new methods that will make sense out of clinical and

    experimental data that can be used to learn and generate rational hypotheses from

    the data and hence to advance the underlying disciplines.



    In this volume we cover some of the topics that are related to this emerging

    and rapidly growing field. In June 11–12, 2010, we organizeda Workshop on

    Optimization and Data Analysis in Biomedical Informatics at the Fields Institute.

    Following this event we gathered invited contributions based on the talks presented

    at the workshop and additional invited chapters from world leading experts. We

    asked the authors to share their expertise in the form of state-of-the-art research

    and review chapters. Our goal was to bring together researchers from different areas

    and emphasize the value of mathematical methods in the areas of clinical sciences.

    This volume is targeted to applied mathematicians, computer scientists, industrial

    engineers, and clinical scientists who are interested in exploring emerging and

    fascinating interdisciplinary topics of research. We hope that this book will stimulate

    and enhance fruitful collaborations between scientists from different disciplines.

    The editors would like to acknowledge the Fields Institute for their financial support

    and hospitality. In addition, we would like to thank all the authors of the invited

    chapters as well as Mrs. Debbie Iscoe for her valuable help during the editing of

    this volume.



    Gainesville,

    FL Waterloo,

    ON Orlando, FL



    Panos M. Pardalos

    Thomas F. Coleman

    Petros Xanthopoulos





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