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Engineering and Manufacturing for Biotechnology - Marcel Hofman & Philippe Thonart

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    Engineering and Manufacturing for Biotechnology - Marcel Hofman & Philippe Thonart









    EDITORS PREFACE

    Early integration of process engineering and biological research is the key for success in

    industrial biotechnology. This is true as well when a selected wild-type organism is put

    to work as when an organism is engineered to purpose.



    Focus on Biotechnology reports on biotechnology achievements in the recent past, but

    also provides a strategic view on the evolution in the next decade. The present volume

    "Engineering and Manufacturing for Biotechnology" took advantage of the European

    Congress on Biotechnology (Brussels, Belgium, July 11-15, 1999) : by topics handled

    and by expertise of the contributors the engineering science symposia of this congress

    offered just what was needed to cover this important topic.



    The editors have solicited the authors of a number of outstanding contributions to

    illustrate the intimate interaction between productive organism and the numerous

    processing steps running from the initial inoculation to the packaged product. Upstream

    processing of the feed streams, selection of medium components, product harvesting,

    downstream processing and product conditioning are just a few major steps. Each step

    imposes a number of important choices. Every choice is to be balanced against time to

    market, profitability, safety and ecology.



    It should be readily apparent from this volume that the development of a truly effective

    biotechnology process requires a broad command of leading-edge engineering science,

    a spark of genius, and last but not least much hard work. That is why the editors wish to

    express their gratitude to all the authors of this volume, for finding the time after busy

    hours at the lab, on the pilot floor or in the production plant to share their experience

    and enthusiasm.



    A final word of esteem is due to all those that through their devoted and outstanding

    secretarial skills have made the edition of this volume possible.



    Marcel Hofman

    Philippe Thonart





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